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Carbaglu

InhA, Func 1188-38-1
产品编号 ABIN3220322
发货至: 中国

Quick Overview for Carbaglu (ABIN3220322)

应用范围

Inhibition Assay (InhA), Functional Studies (Func)
  • 原理

    Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.

    产品特性

    Tradename: Zemuron
    Source of Compound: synthetic
    Target: Amino Acids and Derivatives
    Receptor: Carbamoyl-phosphate synthase

    纯化方法

    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

    纯度

    98 %

    Formula

    C6H10N2O5

    Solubility

    10 mM in H2O
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Solid

    储存条件

    -20 °C

    储存方法

    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

    有效期

    24 months
  • 背景

    Amino Acids & Building Blocks

    分子量

    190.15 g/mol

    CAS-编号

    1188-38-1
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